xCELLigence RTCA CardioECR - 心肌细胞收缩性和电活动
CardioECR 还具有电刺激功能，可通过电刺激促进 hiPSC 心肌细胞成熟。刺激后的 hiPSC 心肌细胞呈现出显著改善的细胞表型，可用于各种研究，包括药物安全性/毒性评估、药物开发和心脏疾病研究。
- RTCA 分析仪
索取报价单
产品详细信息
- 监测兴奋-收缩耦联和离子通道活性
- 生成与致心律失常活动高度相关的数据
- 使用刺激功能进行更为严格可控的分析
- 获得对药物作用机制更深入的了解
- 应用简报
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Cardiotoxicity Assessment of Antiviral Drugs Using the Agilent xCELLigence RTCA CardioECR System
This study used the Agilent xCELLigence RTCA CardioECR system with human iPSC-derived cardiomyocytes (hiPSC-CMs) to evaluate cardiac safety/toxicity of antiviral drugs.
- 应用简报
- English
- 2024 年 5 月 21 日
- 1.55 MB
Multimodal Connected Workflow for Cardiotoxicity Assessment Using Human iPSC-Derived Cardiomyocytes
This application note demonstrates the feasibility and use of combining multiple cell-based in vitro assays from Agilent that use diverse analytical technologies to investigate the cardiac liability of drugs.
- 应用简报
- English
- 2022 年 9 月 26 日
- 1002.14 KB
Connected Workflow: Assessment of Inotropic Compounds in PacedCardiomyocytes Using Calcium Imaging
This app note demonstrates the feasibility of using a connected workflow to evaluate the effect of inotropic compounds on electrically paced human iPSC derived cardiomyocytes (hiPSC-CMs) through calcium imaging
- 应用简报
- English
- 2022 年 6 月 6 日
- 2.93 MB
Assessment of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Disease Models Using the Agilent xCELLigence CardioECR System
A demonstration of the use of the Agilent xCELLigence RTCA CardioECR system to compare functional profiles of contractility and electrophysiology between an PS-iPSC-CM disease model and its isogenic control.
- 应用简报
- English
- 2021 年 9 月 10 日
- 2.82 MB
Using the Agilent xCELLigence RTCA ePacer for Functional Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
This application note presents a method for improving human-induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) maturation using the Agilent xCELLigence RTCA ePacer system.
- 应用简报
- English
- 2021 年 2 月 11 日
- 5.39 MB
A Real-Time Impedance Analysis Instrument for Cardiac Safety and Toxicity Assessment
In this application note, the RTCA Cardio instrument is used with human stem cell-derived cardiomyocytes (iCell Cardiomyocytes) for assessment of the cardiac safety profile of leading compounds or drug candidates during drug development.
- 应用简报
- English
- 2020 年 12 月 4 日
- 2.01 MB
The Agilent xCELLigence RTCA CardioECR System: A Multiparametric Functional Analysis Instrument for Cardiac Safety and Toxicity Assessment
In this application note, we used the xCELLigence RTCA CardioECR system (CardioECR system) in conjunction with hiPS-CMs for the assessment of preclinical cardiac risks.
- 应用简报
- English
- 2020 年 7 月 16 日
- 4.82 MB
- 文献转载
- 产品样本
- 数据表
- 用户手册
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User Guide for iCell Cardiomyocytes Assay on an xCELLigence RTCA CardioECR System
A guide for using the xCELLigence RTCA CardioECR system to analyze iCell cardiomyocytes.
- 用户手册
- English
- 2020 年 8 月 21 日
- 148.23 KB
