xCELLigence RTCA Cardio - 心肌细胞收缩性
xCELLigence RTCA Cardio 仪器以96 孔电极板 (E-Plate Cardio 96) 形式分析细胞，将仪器置于标准 CO2 细胞培养箱中，并通过电缆连接到培养箱外的分析工作站。用户友好型软件可实现对仪器的实时控制和监测。
- RTCA 分析仪
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产品详细信息
- 提供了一种高通量方法，用于检测功能性心脏毒性对短期和长期心脏搏动活性的影响以及一般毒性
- 致心律失常活动的相关研究
- 深入了解化合物的作用机制
- 应用简报
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Cardiotoxicity Assessment of Antiviral Drugs Using the Agilent xCELLigence RTCA CardioECR System
This study used the Agilent xCELLigence RTCA CardioECR system with human iPSC-derived cardiomyocytes (hiPSC-CMs) to evaluate cardiac safety/toxicity of antiviral drugs.
- 应用简报
- English
- 2024 年 5 月 21 日
- 1.55 MB
Multimodal Connected Workflow for Cardiotoxicity Assessment Using Human iPSC-Derived Cardiomyocytes
This application note demonstrates the feasibility and use of combining multiple cell-based in vitro assays from Agilent that use diverse analytical technologies to investigate the cardiac liability of drugs.
- 应用简报
- English
- 2022 年 9 月 26 日
- 1002.14 KB
Connected Workflow: Assessment of Inotropic Compounds in PacedCardiomyocytes Using Calcium Imaging
This app note demonstrates the feasibility of using a connected workflow to evaluate the effect of inotropic compounds on electrically paced human iPSC derived cardiomyocytes (hiPSC-CMs) through calcium imaging
- 应用简报
- English
- 2022 年 6 月 6 日
- 2.93 MB
Assessment of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Disease Models Using the Agilent xCELLigence CardioECR System
A demonstration of the use of the Agilent xCELLigence RTCA CardioECR system to compare functional profiles of contractility and electrophysiology between an PS-iPSC-CM disease model and its isogenic control.
- 应用简报
- English
- 2021 年 9 月 10 日
- 2.82 MB
Using the Agilent xCELLigence RTCA ePacer for Functional Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
This application note presents a method for improving human-induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) maturation using the Agilent xCELLigence RTCA ePacer system.
- 应用简报
- English
- 2021 年 2 月 11 日
- 5.39 MB
A Real-Time Impedance Analysis Instrument for Cardiac Safety and Toxicity Assessment
In this application note, the RTCA Cardio instrument is used with human stem cell-derived cardiomyocytes (iCell Cardiomyocytes) for assessment of the cardiac safety profile of leading compounds or drug candidates during drug development.
- 应用简报
- English
- 2020 年 12 月 4 日
- 2.01 MB
The Agilent xCELLigence RTCA CardioECR System: A Multiparametric Functional Analysis Instrument for Cardiac Safety and Toxicity Assessment
In this application note, we used the xCELLigence RTCA CardioECR system (CardioECR system) in conjunction with hiPS-CMs for the assessment of preclinical cardiac risks.
- 应用简报
- English
- 2020 年 7 月 16 日
- 4.82 MB
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