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Lipidomics Software to Maximize Insight

The complexity and size of lipidomics data sets requires advanced software tools for analysis and conversion to meaningful biological information. Chemometrics data analysis for lipidomics is used to make this conversion. Agilent offers a comprehensive portfolio of software for performing chemometrics, including multivariate analysis for lipidomics. This portfolio of solutions supports both gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS)-based discovery and targeted lipidomics workflows, including data mining, statistical analysis, compound annotation, and pathway visualization. For LC/MS-based profiling of complex lipid samples, lipid annotation is the biggest challenge. Identify lipids by MS/MS spectral library matching with the Agilent MassHunter METLIN Metabolomics Database and Library or by in silico spectral matching using Agilent Lipid Annotator software. In addition, Agilent Mass Profiler Professional can be used to map statistical results from lipidomics experiments onto biological pathways for enhanced analysis, visualization of pathway information, and easier interpretation. 

If you have questions about lipidomics data analysis solutions or would like to be contacted by an Agilent representative, let us know below. 

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Accelerate Your Lipidomics Profiling Workflows

Lipid profiling is comprehensive, designed to yield relative quantitation and identification of hundreds of lipids, including isomers, in a single analysis. Advanced techniques like supercritical fluid chromatography (SFC), 2D-LC, and ion mobility (IM) MS have facilitated lipidomics, but the complex data generated requires similar advancements in data analysis. Learn how Agilent Lipid Annotator software and Mass Profiler Professional can accelerate lipid profiling workflows.



Agilent Lipidomics Data Analysis Solutions

Annotation and Differential Analysis

Discover how Lipid Annotator software can be applied to complex LC/quadrupole time-of-flight (Q-TOF) data to advance drug‑treated AML cell studies.

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Lipid Annotator Software Overview

See how user-friendly Lipid Annotator software provides comprehensive lipids annotation from Q-TOF data.

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Developing Multidimensional Skyline Spectral Libraries

Rapidly and accurately process large Ion Mobility LC/Q-TOF lipid datasets using multidimensional Skyline spectral libraries.

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Data Analysis for Iterative MS/MS Acquisition

Improve coverage in a comprehensive lipidomics workflow using automated, iterative MS/MS Q-TOF acquisition and Lipid Annotator software.

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Informatics for 2D-LC/MS and IM-MS Workflows

Confidently annotate more compounds using 2D-LC lipid separation prior to All Ions IM-MS analysis with advanced data analysis.

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Lipid Annotator Software Workflow

Learn how the Agilent lipidomics software workflow can achieve comprehensive lipid annotation for the study of acute-myeloid-leukemia (AML) cell lines.

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