The 7250 GC/Q-TOF - High Resolution Accurate Mass (HRAM) GCMS
7250 GC/Q-TOF
Whether it is used in complex metabolomics studies, pesticide screening in challenging matrices, or compound identification in herbal extracts, quadrupole time-of-flight GC/MS provides the ultimate in performance. Designed for real-world analysis and built for laboratory robustness, this accurate mass screening GC/MS delivers consistent confidence in results, allowing you to see the whole picture.
- GC/MS Instruments
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Product Details
- Identifies compounds through high-resolution, accurate-mass data and sensitive detection
- Quantifies analytes accurately across a wide dynamic range, without compromising spectral quality
- Simplifies ambiguous data with low-energy EI for softer ionization and molecular ion enhancement (application specific)
- Supports complimentary data types with available chemical ionization for both positive and negative mode analyses
- Increases confidence in compound detection with highly efficient ionization and MassHunter SureMass algorithm for accurate and sensitive extraction of library-quality compound spectra for high match scores
- Enhances compound identification with spectral fidelity for trustworthy library matching and isotopic fidelity for generating verifiable chemical formulas
- Detects trace-level target compounds in the presence of more abundant matrix compounds with a wide in-spectrum dynamic range
- Elucidates chemical structures with MS/MS capabilities and Molecular Structure Correlator software that reveals greater detail
- Ensures excellent data quality even for narrow chromatographic peaks in high-throughput workflows with data acquisition rates of up to 50 spectra per second
- Performs screening, profiling, discovery workflows, and more, using comprehensive MassHunter software
- The built-in intelligence of the 8890 GC drives productivity with diagnostics and monitoring, and simplified access to powerful operations through the integrated touchscreen and browser interface
- Supports both flow and thermally-modulated comprehensive GCxGC for flexibility in enhanced chromatographic resolution for selective compound detection
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Gas Chromatography Mass Spectrometry (GC-MS) Information
What is GC-MS? GC/MS combines two analytical tools to identify and measure the concentration of chemicals found in foods, consumer products, pharmaceuticals, fuels, the environment, and more. Read on to learn more about the typical components of a GC/MS instrument and its basic principle of operation.
Learn More- Application Notes
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Analysis of Volatile Compounds Identified in Rubber Gasket Extracts Using GC/MSD and High-Resolution GC/Q-TOF
This application note establishes a process for identifying GC-amenable extractables and leachable compounds using GC/MSD and GC/Q-TOF instruments.
- Application Notes
- English
- 16 Sep 2024
- 3.27 MB
Analysis of PFAS and Environmental Contaminants in Soil and Oat Plants with GC/Q-TOF
Analysis of PFAS and other environmental contaminants in soil and oat plants using high resolution Agilent 7250 GC/Q-TOF.
- Application Notes
- English
- 08 May 2024
- 1.16 MB
Accurate Mass Library for PFAS Analysis in Environmental Samples
This application note describes the development and use of an accurate mass PCDL of PFAS compounds for the Agilent 7250 GC/Q-TOF.
- Application Notes
- English
- 07 Dec 2023
- 2.24 MB
Differences in Metabolic Profiles of Individuals with Heart Failure Using High-Resolution GC/Q-TOF
This application note describes a GC/Q-TOF untargeted metabolomics workflow that uses the Agilent accurate mass metabolomics PCDL as well as unit mass libraries for compound identification.
- Application Notes
- English
- 16 Nov 2023
- 1.50 MB
Introducing Semi-Automated GC/Q-TOF Screening with the AssayMAP Bravo Sample Prep Platform for Routine Antidoping Control
In this application note, the use of semi-automated GC/Q-TOF screening is described for use in routine antidoping controls, with the use of the AssayMAP Bravo for automated sample prep.
- Application Notes
- English
- 13 Sep 2023
- 2.72 MB
Accurate Mass Metabolomics Library and Its Evaluation in Data Analysis Workflows
This application note evaluates the Agilent Fiehn accurate mass metabolomics personal compound database and library in targeted and nontargeted screening workflows.
- Application Notes
- English
- 30 Mar 2023
- 2.34 MB
Accurate Mass Library for Natural Products Based on Compounds Identified in Hemp Oil
This application note describes the creation of an accurate mass natural products library for GC/Q-TOF MS based on hemp CBD oil comprehensive GC x GC data.
- Application Notes
- English
- 03 Nov 2022
- 1.64 MB
7250 GC/Q-TOF Food and Environmental Application Compendium
Learn how the 7250 GC/Q-TOF enables accurate mass screening by GC/MS and enhanced compound identification through MS/MS, low-energy electron ionization, and complimentary chemical ionization techniques.
- Application Notes
- English
- 10 Nov 2021
- 869.34 KB
Analysis of Extractable and Leachable (E&L) Compounds Using a Low-Energy EI-Capable High‑Resolution Accurate Mass GC/Q-TOF
This work presents a novel tool to study E&L compounds with enhanced flexibility and confidence using a high-resolution accurate mass GC/Q-TOF
- Application Notes
- English
- 30 Oct 2020
- 774.28 KB
Analysis of Wastewater Effluent Samples to Identify Toxic Chemicals Using the High-Resolution Agilent 7250 GC/Q-TOF
This study utilized a workflow for broad-scope suspect screening to identify toxic chemicals in wastewater effluents.
- Application Notes
- English
- 18 Sep 2020
- 2.29 MB
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- Installation Checklists
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7250A Acquisition Installation Checklist
7250A Acquisition Installation Checklist
- Installation Checklists
- English
- 30 Jun 2017
- 163.01 KB
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- Publications
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- Comprehensive characterization of volatile and semi-volatile compounds in e-liquids for electronic cigarette using gas chromatography accurate mass spectrometry. M. Cobo Golpe, et al. Journal of Chromatography A 2023. Learn More
- Chemical characterization and antioxidant, anti-inflammatory, and anti-septic activities of the essential oil from the aerial parts of Atractylodes macrocephala Koidz. L. Wang, et al. Arabian Journal of Chemistry 2022. Learn More
- New analytical method for quantifying flavoring chemicals of potential respiratory health risk concerns in e-cigarette liquids. M. Page and M. Goniewicz. Frontiers in Chemistry (Lausanne, Switzerland) 2021. Learn More
- Separation and qualitative study of Ruta graveolens L. essential oil components by prep-GC, GC-QTOF-MS and NMR. Y. Li, et al. Natural Product Research 2020. Learn More
- Characterization of cabernet sauvignon wines by untargeted HS-SPME GC-QTOF-MS. A. Chavez-Marquez, et al. Molecules 2022. Learn More
- Separation and qualitative study of mentha asiatica boriss. Essential oil components by prep-GC, GC-QTOF-MS, NMR and prediction of bioactive compounds. A. Aimila, et al. Chemistry & Biodiversity 2023. Learn More
Videos
High Resolution GC/Q-TOF for Routine Analysis of Dioxins and Targeted and Untargeted Screening in Environmental Matrices
Gas chromatography with quadrupole time-of-flight mass spectrometry (GC/Q-TOF) is a highly versatile tool capable of doing routine chemical quantification of regulated compounds while also performing non-targeted identification of emerging pollutants in environmental samples.
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