Multiple Heart-Cutting 2D-LC
1290 Infinity III 2D-LC System
For applications in biopharma, pharma, chemical and other industries with demanding conditions with respect to solvents, samples and reagents, use the 1290 Infinity III Bio 2D-LC System with biocompatible or bio-inert LC modules and biocompatible 2D-LC valves and sample loops.
Use multiple heart-cutting 2D-LC to solve complex separations, and comprehensive 2D-LC to analyze complex samples with many compounds. This technology offers the proven robustness of Agilent 1290 Infinity III systems, and with the Easy Start Service it is easier than ever to get the full 2D experience.
- 2D-LC Solutions
Product Details
- From separation of a few co-eluting compounds to mixtures of highest complexity - Agilent 2D-LC solutions allow you to do 2D-LC your way, choosing from 2D-LC modes (multiple) heart-cutting with high-resolution sampling and comprehensive 2D-LC
- Set up measurements easily with powerful Agilent 2D-LC software. Start with your 1D measurement, choose spots where you want to increase resolution, draw your second dimension gradient, and go
- Get all the information you need from your sample from qualitative results, including spectral data up to reproducible quantitative results
- Use 1290 Infinity III Systems and dedicated 2D-LC valve technology for UHPLC performance, fast gradients, high sensitivity, and excellent robustness
- Combine first and second dimension solvents and gradients as you like using Agilent Active Solvent Modulation Technology
- Replace multiple one-dimensional separations by one two-dimensional separation for better results in less time
- Upgrade your Agilent 1290 Infinity III LC System (1-D) easily to 2D-LC system for better resolution
- Use the 1290 Infinity III Bio 2D-LC system for applications in biopharma, pharma, chemical and other industries that use samples, that require minimum surface binding and metal ion elution or use solvents or reagents over a wide pH range or with high salt concentrations. Materials like MP35N, ceramics, PEEK or gold are known for excellent characteristics under such conditions and are used in the entire flow path of Agilent biocompatible LC systems.
- Learn basic and advanced 2D-LC functionality with the Agilent Easy Start Service to realize the full power of 2D-LC. Key qualitative and quantitative workflows are explained and demonstrated in the customers lab. This includes 2D method setup and development, data analysis and reporting, system configuration and instrument control. Easy Start Service is available in 2-or 3-day flavors covering one or multiple workflows for different software products including 2D-LC Software for OpenLab CDS, MassHunter and ChemStation and GC Image Software LC x LC Edition.
- Start working with 2D-LC today using application notes in many areas such as pharmaceuticals, biopharmaceuticals, chemicals, fuels, food, and many others
- Your choice for performance and sustainability: The 1290 Infinity III LC System has received the My Green Lab ACT (Accountability, Consistency, Transparency) label after an independent audit to verify its environmental impact throughout the product life cycle.
- Mobile Phase Delivery
-
1290 Infinity III Bio High-Speed Pump
Biocompatible binary solvent delivery at pressures up to 1300 bar and flow rates up to 5 mL/min
1290 Infinity III High Speed Pump
Binary solvent delivery at pressures up to 1300 bar and flow rates up to 5 mL/min.
- Sample Introduction
- Column Handling
- Detection
- Fraction Collection
- Recommended Accessories
- Application Software
- Key Literature
-
Two-Dimensional Liquid Chromatography
Describes the fundamental principles, practical implementation and applications where 2D-LC has been proven indispensable.
- Primers
- English
- 09 Jun 2015
- 9.44 MB
LCGC Executive Summary: Simplify Complex Separations. Fast.
This executive summary gives you an overview of how to separate coeluting compounds, analyze complex samples fast, or simplify tedious separation workflows with 2D-LC.
- White Papers
- English
- 01 Feb 2019
- 1.12 MB
High-Resolution Sampling 2D-LC for Pharmaceutical Impurity Analysis
The detection of low-level impurities contained in a sample of a structurally related main compound using high‑resolution sampling 2D-LC is shown.
- Application Notes
- English
- 14 Oct 2024
- 2.05 MB
- Application Notes
- Article Reprints
- Brochures
- Data Sheets
- Posters
- Technical Overviews
- White Papers
- FAQs
-
HPLC Fundamentals and FAQs
Learn HPLC and UHPLC basics and principles, including frequently asked questions, to help you be confident in your HPLC results. Read HPLC fundamentals now.
- User Manuals
- Publications
-
- Complexity Begets Collaboration. With new achievements and changes every month—from personalized medicines to artificial intelligence and automation—it is becoming increasingly challenging for the biopharmaceutical industry to keep up. The Analytical Scientist spoke with Jennifer Römer, an expert in mass spectrometric protein characterization at Rentschler Biopharma SE in Laupheim, Germany—a contract development and manufacturing organization for biopharmaceuticals, including advanced therapy medicinal products—as well as Jens Meixner, product manager for CE and HPLC systems at Agilent, to find out more about the challenges faced by users and manufacturers in a rapidly evolving world.
The publication date: 05/24/2024 Learn More
- Complexity Begets Collaboration. With new achievements and changes every month—from personalized medicines to artificial intelligence and automation—it is becoming increasingly challenging for the biopharmaceutical industry to keep up. The Analytical Scientist spoke with Jennifer Römer, an expert in mass spectrometric protein characterization at Rentschler Biopharma SE in Laupheim, Germany—a contract development and manufacturing organization for biopharmaceuticals, including advanced therapy medicinal products—as well as Jens Meixner, product manager for CE and HPLC systems at Agilent, to find out more about the challenges faced by users and manufacturers in a rapidly evolving world.
Read reviews on the 1290 Infinity II 2D-LC
Explore customer reviews posted on Select Science, or write your own review.
Agilent InfinityLab HPLC Advisor
This one comprehensive app provides tools and information for your daily HPLC workflow.
Essential Supplies Guide for InfinityLab LC Series Instruments
Discover the right supplies for your instrument to achieve peak performance and optimize your LC workflow.
HPLC/UHPLC Upgrades
Discover how you can enhance your lab efficiency and upgrade your existing HPLC/UHPLC systems and components.