Enable characterizing key complexes involved in mitochondrial function
This exclusive reagent is a recombinant protein capable of forming pores in cytoplasmic membrane via oligomerization, leading to permeabilization of cultured cells. This action is consistent and highly specificity towards cytoplasmic membrane without damaging mitochondrial membranes. It enables detailed characterization of drug effect or substrate oxidation impact on the function of a specific mitochondrial component (e.g. transporters, enzymes and ETC complexes), without the need to isolate mitochondria.