xCELLigence RTCA eSight Instrument including Workstation
xCELLigence RTCA eSight - Imaging & Impedance
- RTCA Analyzers
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Product Details
- Combine label-free xCELLigence Real-Time Cell Analysis technology with live-cell imaging in red, green, and blue spanning 5, 10, and 20x objectives for increased confidence in your cell analysis and conclusion
- Whole well imaging expansion: Visualize the entire well when doing QC or quantifying and monitoring cell growth
- Multiplexed and information-rich assays combining cellular impedance and imaging in the same well, all inside your incubator
- Deliver physiologically relevant data whether 2D or 3D based cell cultures, with a simple workflow that adapts to differing experimental protocols while monitoring cell health, behavior, and function
- Utilize flexible live-cell imaging brightfield capabilities and three fluorescent channels spanning a multitude of microplate forms (6-, 12-, 24-, 48-, 96-, or 384- well) and vessel types (35 or 60 mm dishes), and the capability of user-defined schedules
- Analyze a continuous readout of cell number, proliferation size, cell size/shape, changes to morphology, and cell-substrate attachment quality
Single Setup for Dual Measurements
Live cell imaging and real-time biosensor measurements can be performed on the same cell populations, which provides insightful information on cell behavior. The streamlined workflow, high reproducibility, and quantitative kinetics of the eSight system makes it ideal for a wide range of cell-based assays such as proliferation, cytotoxicity, and apoptosis.
Learn MorePatented Real Time Cell Analysis
The impedance-based xCELLigence technology utilizes proprietary microplates (E-Plates) embedded with gold biosensors at the bottom of each well, which serve to non-invasively quantify cell behavior. Over the course of an experiment, the biosensors monitor cell metrics such as proliferation, adhesion strength, changes in morphology, migration, differentiation, and much more.
Learn MoreExpanded eSight Capabilities and Live-Cell Imaging Applications
Generate highly reproducible data and derive more meaningful biological insights- all inside your incubator. Investigate a wide range of cell models on the eSight. Now introducing Dilution Cloning, Scratch Wound Healing, Immunotherapy, Cell-by-Cell Analysis, 3D Spheroid Invasion and Immune Cell Killing applications.
Learn More- Key Literature
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Measure Cell Movement, Health, and Function With xCELLigence RTCA eSight
Multiparametric real-time automated readouts using simultaneous cellular impedance and live cell imaging.
- Brochures
- English
- 22 Nov 2024
- 10.55 MB
General xCELLigence brochure
xCELLigence Real-Time Cell Analysis Instruments
- Brochures
- English
- 18 Nov 2021
- 7.89 MB
- Application Notes
- Article Reprints
- Data Sheets
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- Instruction Sheets
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Dell Ownership Transfer Process
Dell Ownership transferring process
- Instruction Sheets
- English
- 24 Aug 2020
- 417.41 KB
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Dr. Zelia Geouveia
Institut Curie
We are a laboratory working in cancer research, namely chimeric antigen receptor (CAR)-T cells targeting different antigens in the tumor. We were seeking a high throughput platform that would allow us to evaluate CAR-T cells killing in real-time. We were also interested in visualizing the killing in real time. The xCELLigence RTCA eSight was one of the technologies that could provide such information using impedance and live cell imaging (one machine, two different and precious information). When compared with other instruments that could provide imaging information only, the image quality was similar but we would not have the impedance for comparison. Thus, we decided that having both
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