Chem Elut S (Synthetic)
SLE cartridges differ from other cartridge-based extractions, like solid phase extraction (SPE), because the original sample is loaded onto the extraction bed and is not intended to flow through. Therefore, Agilent SLE cartridge and well plate formats are named according to the sample capacity, not bed mass. It is very important to choose the appropriate format based on your total loading sample volume.
For years, diatomaceous earth material has been used for SLE extractions. Since diatomaceous earth is mined, not manufactured, it is difficult to control particle size which can compromise results. Chem Elut S, a synthetic SLE extraction product, has a controlled particle size and delivers consistent flow and uniformity in every batch. This improves reproducibility by minimizing analyst-to-analyst and batch-to-batch variability.
Compared to time-consuming and labor-intensive liquid-liquid extraction, SLE extraction with Chem Elut S reduces analyst-to-analyst variability, improves matrix removal, and requires minimal extraction solvent, which leads to increased analyte concentration. Chem Elut delivers reliable, reproducible results with minimal method development and a walk-away workflow.