Solid phase microextraction (SPME) is a solvent-free sample preparation technology. Based on the principle of adsorption or absorption and desorption, SPME uses a coated fiber or Arrow to concentrate volatile and semivolatile compounds from a sample. In SPME, analytes establish equilibria among the sample matrix, the headspace above the sample, and the polymer-coated fused phase. There are two categories of SPME extractions: headspace (most common) and direct immersion (DI), where the SPME fiber or Arrow is immersed into the aqueous sample (application specific).
Solid Phase Microextraction (SPME) for Solvent-Free Sample Preparation