1260 Infinity III Prime Online LC System
This online LC process analysis system also features retain-sample functionality for dilutions or automated sample preparation steps, multimethod analysis, or sample archiving purposes for offline quality control.
- Online LC Solutions
Product Details
- Dedicated process analytical technology (PAT) tool for online and at-line process analysis via LC applications
- Enables fast process monitoring of critical process parameters (CPPs) and critical quality attributes (CQAs) via direct injections, providing real-time data for greater control and faster understanding of processes
- Features retain-sample functionality for dilutions (including reaction quenching), multimethod analysis, automated sample preparation, additional offline quality control, or sample archiving purposes
- Brings hybrid injection technology to the LC world: Both classical flow-through injection and Agilent Feed Injection are supported, guaranteeing seamless method transfer and the capability to mediate strong sample diluent effects via Agilent Feed Injection
- Enables utmost control over the process sample and facilitates method development
- Coordinates sampling and sample analysis via Agilent Online LC Monitoring Software, compatible with OpenLab CDS 2 and designed for process applications
- Online LC Monitoring Software allows for intuitive sample scheduling to quickly set up sampling events, and provides data visualization tools such as trending plots to easily monitor the process
- Supports flow rates up to 5 mL/min within a pressure range up to 800 bar for maximum application flexibility
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- Sample Introduction
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1260 Infinity III Online Sample Manager
Direct injections and retain-sample functionality for fast, confident process monitoring.
- Recommended Accessories
- Key Literature
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Performance Evaluation of a Reactor Sampling Device for Online LC
In this technical overview, the use of the Agilent 1260 Infinity II Prime Online LC System connected to a Mettler Toledo EasySampler 1210 is made possible through the Snapdragon Chemistry Sample Relay System to form a sampling device.
- Technical Overviews
- English
- 14 Oct 2024
- 719.60 KB
Online Monitoring of a Heterogenic Liquid/Liquid Reaction
This application note will describe the combination of the Agilent 1260 Infinity II Online LC with the Mettler Toledo EasySampler 1210, using the Snapdragon Chemistry’s SRS module, for monitoring of heterogenic reactions.
- Application Notes
- English
- 14 Oct 2024
- 357.70 KB
Online LC Monitoring of Hydrolysis of Organic Acid Esters by Means of Flow Chemistry
In this application note, a method is described for the monitoring of a flow chemistry reaction using the Agilent 1260 Infinity II Prime Online LC System.
- Application Notes
- English
- 14 Oct 2024
- 587.83 KB
- Application Notes
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HPLC Fundamentals and FAQs
Learn HPLC and UHPLC basics and principles, including frequently asked questions, to help you be confident in your HPLC results. Read HPLC fundamentals now.
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- Parallel experiments in electrochemical CO2 reduction enabled by standardized analytics.
Contributors: Alessandro Senocrate, Francesco Bernasconi, Peter Kraus, Nukorn Plainpan, Jens Trafkowski, Fabian Tolle, Thomas Weber, Ulrich Sauter, & Corsin Battaglia. 26 June 2024
Learn More - Expediting online liquid chromatography for real-time monitoring of product attributes to advance process analytical technology in downstream processing of biopharmaceuticals. Tobias Graf, Lukas Naumann, Lea Bonnington, Jakob Heckel, Bernhard Spensberger, Sascha Klein, Christoph Brey, Ronnie Nachtigall, Maximilian Mroz, Thomas Vagn Hogg, Christopher McHardy, Andres Martinez, Reinhard Braaz & Michael Leiss. 16 August 2024 Learn More
- Parallel experiments in electrochemical CO2 reduction enabled by standardized analytics.
Agilent InfinityLab HPLC Advisor
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Essential Supplies Guide for InfinityLab LC Series Instruments
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Videos
Integrated Real-Time PAT, Modeling, and Process Control Strategies to Enable Production of Glycosylated Biologics
Biotherapeutics represent a growing class of pharmaceuticals with specific challenges in the discovery and development process. Learn about technological and scientific advances to support safe and effective development of biotherapeutics.
Collaboration with APC on Real-Time Process Monitoring
Agilent announced a collaboration agreement with APC Ltd., in which the companies commit to working towards combining their technologies to provide unique workflows to customers that support automated process analysis via liquid chromatography (LC).
- Collaboration with APC on Real-Time Process Monitoring
- 28 Sep 2022