Neuron-specific enolase is one of three main groups of enolases, the other two being non-neuronal enolase and muscle-specific enolase. The antibody labels cells of neuronal and neuroendocrine origin. Although neuron-specific enolase is not an exclusive neuronal marker, it may be used for the identification of peripheral nerves. Results aid in the classification of neural and neuroendocrine tumors, such as neuroblastomas, retinoblastomas, desmoplastic malignant melanoma, and small-cell lung cancer.
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Product Details
Features
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Specifications
Application
Formalin
HIER
Clone
BBS/NC/VI-H14
Code Number
IR612
Immunogen
γγ-enolase purified from human brain by a dissociation-reassociation method in a chromatofocusing column (1). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions
Autostainer Link 48
Species
Mouse Anti-Human
Specificity
In Western blotting of reduced, SDS-denatured purified human γγ-enolase, αα-enolase, and extract of human muscle containing ßß-enolase, the antibody labels solely the γ-enolase subunit (1). See package insert for reference(s).