Breast ductal carcinoma

Mammaglobin (Dako Omnis)

Clone 304-1A5

Mammaglobin, a 93-amino acid glycoprotein, is encoded by a gene first identified in a study directed at the isolation of novel human breast cancer-associated genes (1). Mammaglobin expression is mostly, although not exclusively, confined to breast tissue, and anti-mammoglobin is a useful aid for the classification of carcinomas of breast origin.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.

Specifications


Application	Formalin HIER
Clone	304-1A5
Code Number	GA074
Immunogen	Purified mammaglobin recombinant protein, containing amino acids 15-93 (4). See package insert for reference(s).
Isotype	IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions	Dako Omnis
Species	Mouse Anti-Human
Specificity	In Western blotting of lysates of breast carcinoma cell line MDA-MB-415, primary breast tumor cell line 450-17 and recombinant mammaglobin the antibody labeled bands of 14 kDa and 21 kDa. The 9 kDa form of mammaglobin was observed after enzymatic deglycosylation of MDA-MB-415 indicating glycosylation of the mammaglobin protein (4). In ELISA no reaction was found with overlapping peptides corresponding to the mammaglobin sequence indicating a conformational epitope. See package insert for reference(s).

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Featured References

Product Description References: 1. Watson MA, Dintzis S, Darrow CM, Voss LE, DiPersio J, Jensen R, et al. Mammaglobin expression in primary, metastatic, and occult breast cancer. Cancer Res 1999,59:3028-31.

Featured

Mammaglobin (Dako Omnis)

Product Details

Atlas of Controls

View supported Instructions For Use documents

1. Watson MA, Dintzis S, Darrow CM, Voss LE, DiPersio J, Jensen R, et al. Mammaglobin expression in primary, metastatic, and occult breast cancer. Cancer Res 1999,59:3028-31.

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