Granulosa cell tumor

Inhibin α (Autostainer Link 48)

Clone R1

Inhibin is a dimeric glycoprotein hormone comprised of an α and a β subunit. It is produced by ovarian granulosa cells and inhibits the production or secretion of pituitary gonadotropins, particularly follicle-stimulating hormone. The antibody was raised against the terminal 1-32 amino acid sequence of the inhibin α subunit. The antibody is a useful aid for classification of sex-cord-stromal tumors.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

Specifications


Application	Formalin HIER
Clone	R1
Code Number	IR058
Immunogen	Synthetic peptide corresponding to the 1-32 amino terminal peptide of the alpha subunit of human 32K inhibin (1). See package insert for reference(s).
Isotype	IgG2a, kappa
Reagent Provided	Ready-to-use monoclonal antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN₃.
Solutions	Autostainer Link 48
Species	Mouse Anti-Human
Specificity	Clone R1, according to inhibition results from radioimmunoassay, demonstrates a much greater preference for human 1-32 than for bovine (73 fold) or porcine (23 fold) peptides. The antibody also reacts with some of the multiple molecular forms of inhibin found in both bovine and human follicular fluids (1). See package insert for reference(s).

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Inhibin α (Autostainer Link 48)

Product Details

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