Reacts with the 68 kDa, 58 kDa, 56.5 kDa and 50 kDa proteins corresponding to cytokeratins 1, 5, 10 and 14. The antibody labels squamous, ductal and complex epithelia. Results aid in the classification of prostatic adenocarcinoma and in the classification of neoplastic tissue as carcinoma of epithelial origin.
This product is not available for purchase by the general public.
Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Formalin
HIER
Clone
34βE12
Code Number
M0630
Immunogen
Solubilized immunogen keratin extracted from human stratum corneum (1). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as tissue culture supernatant in 0.05 mol/L Tris-HCl, pH 7.2 and 0.015 mol/L sodium azide. This product contains stabilizing protein.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
Anti-Cytokeratin, High Molecular Weight (Anti-CK HMW), 34βE12 has been shown to react with the 66, 57, 51 and 49 kDa proteins in Western blotting corresponding to cytokeratins 1, 5, 10 and 14 of the Moll catalog (1, 2, 4). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.