![CD42b CD42b](/cs/publishingimages/Flow_Cytometry_Default_2.jpg)
CD42b
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CD42b is a 145 kDa protein expressed on platelets and megakaryocytes. CD42a, CD42b, CD42c and CD42d form a complex in the platelet plasma membrane which serves as a receptor for von Willebrand factor and thrombin, and mediates adhesion of platelets to subendothelial matrices exposed upon damage to the endothelium. Absence of the CD42 complex leads to the Bernard-Soulier syndrome. The binding sites for von Willebrand factor and thrombin lies on CD42b.
Further information and references to relevant literature are available in the products Instructions For Use.