CD103

Anti-human CD103 antibodies for use in flow cytometry. These single-color reagents are of value to the study of intraepithelial and mucosa-associated CD8-positive T cells, rare resting blood lymphocytes as well as some leukemias and lymphomas.

CD103 is the αE integrin subunit of the heterodimeric αEß7 integrin belonging to a small ß7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia, the cells express CD103. References to literature available in the product’s Instructions For Use.