SurePrint G3 ISCA (Enhanced) Microarrays
The Agilent SurePrint G3 ISCA v2 CGH and CGH+SNP microarrays are dual-color chromosomal microarrays containing 60-mer high quality probes. These are high-resolution tools for genome-wide DNA copy number variation profiling, and +SNP option to capture copy-neutral loss of heterozygosity (cnLOH), without amplification or complexity reduction. Choose from multiple designs that allow for overall median probe spacing of 25kb to 75kb. In addition, each microarray contains a range of internal quality control features to ensure your experiments are successful.
For Research Use Only. Not for use in diagnostic procedures.
Product Details
Features
- ISCA v2 CGH+SNP 4x180K is designed with 25.3KB overall median probe spacing and 5.3KB on ISCA regions. The microarray includes 110,712 (CGH) and 59,647 (SNP) distinct biological features
- ISCA v2 CGH 2x105K Microarray is designed with 35KB genome-wide median probe spacing and enhanced coverage on ISCA regions. The microarray includes 19,647 distinct biological features in ISCA regions and 80,757 backbone probes
- ISCA v2 CGH 4x180K Microarray offers 25 KB overall median probe spacing and enhanced coverage on ISCA regions. The microarray includes 21,445 distinct biological features in ISCA regions and 125,061 backbone probes
- ISCA v2 CGH 4x44K Microarray is designed with 75KB overall median probe spacing and enhanced coverage on ISCA regions. The microarray includes 21,445 distinct biological features in ISCA regions and 125,061 backbone probes
- ISCA v2 CGH 8x60K Microarray is designed with 60 KB overall median probe spacing and enhanced coverage on ISCA regions. The microarray includes 18,851 distinct biological features in ISCA regions and 40,208 backbone probes
- Designs labeled Unrestricted are made to order and qty 1 is a single glass slide
Featured References
- Publications
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- Chromosomal microarray analysis of Bulgarian patients with epilepsy and intellectual disability. Peycheva V, Kamenarova K, Ivanova N, Stamatov D, Avdjieva-Tzavella D, Alexandrova I, Zhelyazkova S, Pacheva I, Dimova P, Ivanov I, Litvinenko I, Bozhinova V, Tournev I, Simeonov E, Mitev V, Jordanova A, Kaneva, R. Gene. 2018 Aug 15;667:45-55. doi: 10.1016/j.gene.2018.05.015. Epub 2018 May 9. [Application: Postnatal] Learn More
- Pinto D et al. Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants. Nat Biotechnol. 2011 May 8;29(6):512-20. doi: 10.1038/nbt.1852 [Application: General] Learn More
- Alesi V et al. Easychip 8x15k: A New Tool for Detecting Chromosome Anomalies in Low Risk Pregnancies, Supporting and Integrating Standard Karyotype J Genet Syndr Gene Ther 7: 277. doi:10.4172/2157-7412.1000277 [Application: Prenatal] Learn More
- Chau MHK et al. Characteristics and mode of inheritance of pathogenic copy number variants in prenatal diagnosis. Am J Obstet Gynecol. 2019 Nov;221(5):493.e1-493.e11. doi: 10.1016/j.ajog.2019.06.007. Epub 2019 Jun 14. [Application: Prenatal] Learn More
