xCELLigence RTCA S16 - Pilot Scale
The instrument operates in a standard CO2 cell culture incubator and the control unit is housed outside the incubator. User friendly software allows for real-time control and monitoring of the instrument with real-time data analysis functions.
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Product Details
- Obtain continuous cell assay time points during the entire experiment.
- RTCA provides a continuous quantitative readout of cell number, proliferation rate, cell size/shape, and cell-substrate attachment quality.
Cellular Impedance Explained
The functional unit of a cellular impedance assay is a set of gold microelectrodes fused to the bottom surface of a microtiter plate well. When submersed in an electrically conductive solution (such as buffer or standard tissue culture medium), the application of an electric potential across these electrodes causes electrons to exit the negative terminal, pass through bulk solution, and then deposit onto the positive terminal to complete the circuit.
Learn More- Application Notes
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xCELLigence Portfolio Cancer Immunotherapy Handbook
Recently updated Cancer Immunotherapy Handbook featuring the latest high impact xCELLigence publications and newly released supporting information.
- Application Notes
- English
- 10 Mar 2023
- 10.21 MB
A New Way to Monitor Virus-Mediated Cytopathogenicity
This application note describes the experimental setup for assessing vesicular stomatitis virus-mediated cytotoxicity of Vero E6 cells and HEK 293 cells using an xCELLigence instrument.
- Application Notes
- English
- 12 Feb 2021
- 358.59 KB
Label-Free Assay for NK Cell‑Mediated Cytolysis
In this application note, a series of experiments demonstrate how the xCELLigence RTCA system can be applied to quantitatively monitor NK cell‑mediated cytolysis without labeling the target cells.
- Application Notes
- English
- 12 Feb 2021
- 699.12 KB
Dynamic Monitoring of Receptor Tyrosine Kinase Activation in Living Cells
This application note highlights the development and utility of an alternative receptor tyrosine kinase assay that uses the impedance‑based xCELLigence system.
- Application Notes
- English
- 12 Feb 2021
- 1.58 MB
Dynamic Monitoring of G-Protein‑Coupled Receptor Activation in Living Cells
In this application note, a series of experiments demonstrates how the xCELLigence system may be used to monitor functional activation of GPCRs in living cells.
- Application Notes
- English
- 12 Feb 2021
- 1.07 MB
Real-Time and Dynamic Monitoring of Cell Proliferation and Viability for Adherent Cells
This application note shows experiments that were conducted using xCELLigence instruments to assess cell proliferation and drug interaction with different cell lines.
- Application Notes
- English
- 19 Aug 2020
- 1.00 MB
Vaccine and Virology Applications
A collection of studies showing the benefits of xCELLigence RTCA assays over traditional assays. Antiviral drugs, virucides, neutralizing antibodies and other applications are examined.
- Application Notes
- English
- 02 Jul 2020
- 4.37 MB
Infectious Disease Applications
A compilation of studies demonstrating the application of xCELLigence RTCA to the analysis of bacterial toxins, biofilms, virus titer determination, and other areas of disease.
- Application Notes
- English
- 02 Jul 2020
- 4.93 MB
Studying Bacterial Biofilms Using Cellular Impedance
Describes the use of Agilent xCELLigence real-time cell analysis (RTCA) instruments for impedance monitoring.
- Application Notes
- English
- 02 Jul 2020
- 1.94 MB
- Article Reprints
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Dell Ownership Transfer Process
Dell Ownership transferring process
- Instruction Sheets
- English
- 24 Aug 2020
- 417.41 KB
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