Columns and Standards for Oligonucleotide HPLC Analysis
AdvanceBio oligonucleotide HPLC columns offer the robustness necessary for successful HPLC oligonucleotide analysis at high pH. AdvanceBio columns have high resolving power and are robust enough to withstand challenging conditions to successfully separate trityl-off, deprotected oligonucleotides,
AdvanceBio Spin Columns address the need for efficient sample preparation of proteins or oligonucleotides under aqueous conditions, preserving native structure with suitable ionic strength and pH. Users can easily and quickly remove excess salts or undesired small molecules from their sample matrix or exchange the sample matrix between different buffer conditions. These gel-filtration-based spin columns are available in analytical and semipreparative scale columns for single samples, as well as 96-sample plates for high-throughput settings.
The free Glycan Peak Assignment Tool was developed to provide additional confidence in identifying InstantPC- or 2-AB-labeled N-glycan peaks by predicting retention times of over 100 glycans. The new tool does not require users to upload sensitive data from N-glycan samples.