Exoglycosidases
Exoglycosidases are glycoside hydrolase enzymes that cleave the glycosidic bonds at the terminal residues. These enzymes are useful in the study of isolated glycans, glycolipids, glycoproteins. Linkage-specific exoglycosidases may also be used for sequencing of oligosaccharides. When used in combination, exoglycosidases enable flexible analytical tools for glycan analysis.
- Glycobiology Enzymes for N-Glycan Workflows
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These enzymes are useful in the study of isolated glycans, glycolipids, glycoproteins, or sequencing studies, especially when used in combination.
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N-Glycan Analysis: Better Together
Push your Glycoprotein analysis to new levels of performance.
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- 18 Mar 2022
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The Importance of Glycan Analysis and Characterization for Biopharma
Professor Michael Butler, head of the National Institute for Bioprocessing Research and Training (NIBRT) Cell Technology Group (CTG), explains that the characterisation and analysis of glycans is important for the biopharma sector as it can help in the development of therapeutic agents, such as monoclonal antibodies and other recombinant proteins. These are used in therapies in a range of serious conditions including cancer, inflammatory diseases, and cardiovascular diseases. The mechanism of action depends upon their strong affinity to molecular targets associated with disease.
- Drug Discovery World (DDW)
- 10 Oct 2022
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