We offer a complete suite of ion exchange columns for charge variant analysis, including weak anion exchange, weak cation exchange, strong anion exchange, and strong cation exchange. Agilent Bio mAb is a weak cation exchange column that has been optimized for charge variant analysis of monoclonal antibodies.
AdvanceBio Spin Columns address the need for efficient sample preparation of proteins or oligonucleotides under aqueous conditions, preserving native structure with suitable ionic strength and pH. Users can easily and quickly remove excess salts or undesired small molecules from their sample matrix or exchange the sample matrix between different buffer conditions. These gel-filtration-based spin columns are available in analytical and semipreparative scale columns for single samples, as well as 96-sample plates for high-throughput settings.
The free Glycan Peak Assignment Tool was developed to provide additional confidence in identifying InstantPC- or 2-AB-labeled N-glycan peaks by predicting retention times of over 100 glycans. The new tool does not require users to upload sensitive data from N-glycan samples.