安捷伦早期职业生涯教授奖
Agilent congratulates Gary J. Patti, winner of the 2017 Agilent Early Career Professor Award
2017 Focus: Contributions to the development and advancement of techniques for the detection of nucleic acids, proteins, or other biomolecules in the context of Liquid Biopsy and its utilization for early detection, characterization and surveillance of cancer and other diseases and conditions.
Gary J. Patti, Ph.D.
Associate Professor, Department of Chemistry
Arts and Science
Washington University in St. Louis
Dr. Patti received a B.A. in Chemistry and Philosophy from Saint Louis University in 2002 and a Ph.D. in Chemistry from Washington University. He then conducted his Postdoctoral work at the Scripps Research Institute in La Jolla, in Dr. Gary Siuzdak's laboratory from 2008 to 2011. There he was involved in the development of widely used metabolomics informatic resources such as the METLIN metabolite database and XCMS software for data processing.
Dr. Patti joined Washington University as Assistant Professor in 2011, with joint appointments in Chemistry (Arts & Sciences) and Genetics (School of Medicine). His lab has published 51 papers and has received numerous grants and awards. His lab has focused on developing new technologies for following isotope labels in untargeted metabolomics. These isotope-based resources have a rapidly increasing number of uses, including clinical applications. Additionally, his laboratory has created other innovative metabolomic technologies that include a new peak picking algorithm, software for deconvolving contaminated spectra, and a method for removing artifacts. The application of these metabolomic technologies has led to two major biochemical discoveries, the finding of a previously unknown metabolite uniquely increased in patients suffering from chronic pain and the discovery that cancer cells utilize lactate to synthesize a large fraction of their lipids. Lactate has long been thought of as a waste product in fermenting cells, but his lab has shown that it is imported into mitochondria for productive use.
The current major goal of his research program is to continue to develop new metabolomic technologies to overcome current barriers to study human disease and model animals in the context of organismal biology. The innovative solutions that his lab is pursuing rely heavily on measuring stable isotopes incorporated into metabolites, proteins, and DNA by mass spectrometry and are aimed at the identification of metabolic changes in body fluids associated with cancer.
His outstanding work has been recognized by many awards including the Pew Biomedical Scholars award, the Camille Dreyfus award, the Sloan Foundation award, the Mallinkcrodt Scholars awards. (press release)
设奖目的
- 促进和鼓励对安捷伦科技公司乃至世界有重要测量意义的研究
- 使安捷伦研发人员与杰出教授在其职业生涯早期就建立密切的合作关系
- 体现安捷伦对大学研究的支持
选择标准
- 对安捷伦科技公司乃至世界有重要测量意义的原创性研究贡献
- 具有在未来继续开展研究的突出潜力
- 符合奖项的指定研究领域
- Professor completed Ph.D. or M.D. less than 10 years before January 1, 2017.
奖项信息
- An unrestricted research award of $100,000 distributed over 2 years to university in the professor's name
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- 可以选择加速奖金的支付,以方便采购标价超过 100000 美元的设备
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2018 年 ECPA 奖
- Award focus, instructions and deadlines will be posted in October 2017.