安捷伦思想领袖计划

Dr. Ram Sasisekharan
Alfred H. Caspary Professor of Biological Engineering and Health Sciences & Technology
Massachusetts Institute of technology
Cambridge, MA

Awarded in April 2017

Dr. Sasisekharan has been a professor of biological engineering at MIT since 1996, and has served as the director of the Harvard-MIT Division of Health Sciences & Technology from 2008-2012. The Sasisekharan lab employs multidisciplinary strategies to develop and integrate orthogonal analytical technologies to further research into complex biopharmaceuticals. The lab originated its efforts with GAGs (such as heparin) to develop analytical and enzymatic tools with the pertinent and defined substrate-product profiles required to understand their structure-function relationships. Timely development and characterization of therapeutic mAb to treat infectious diseases and cancer are currently of paramount interest to his lab. Dr. Sasisekharan has been recognized by numerous accolades and awards, and his ideas and concepts have been the founding basis of many biotechnology companies. (press release)

Dr. Dwight R. Stoll
Associate Professor of Analytical Chemistry
Co-chair of the Chemistry Department
Gustavus Adolphus College
Saint Peter, Minnesota

Awarded in March 2017

Dr. Stoll is widely recognized for his efforts and contributions to analytical chemistry and separation sciences. His active research projects include the development of rapid multidimensional liquid chromatography for targeted and untargeted analysis in complex matrices and optimization of isocratic and gradient elution HPLC. He has pioneered the development of 2D-HPLC and its applications in BioPharma.

Dr. Stoll has received numerous awards and recognitions including the John B. Phillips Award for contributions to multidimensional gas chromatography, the LCGC’s Emerging Leader in Chromatography Award. In 2014 he was named to The Analytical Scientist’s list of ‘Top 40 Under 40’ analytical scientists and received the American Chemical Society Division of Analytical Chemistry Award for Young Investigators in Separation Science in 2015. In 2016 he received the Palmer Award from the Minnesota Chromatography Forum and the Gustavus Faculty Scholarly Achievement. Earlier this year he received the Eastern Analytical Symposium Young Investigator Award. (press release)

Shane A. Snyder 博士
Professor - Chemical and Environmental Engineering
Co-Director of the Arizona Laboratory for Emerging Contaminants (ALEC) and the Water & Energy Sustainable Technology (WEST) Center
University of Arizona
Tucson, AZ

获奖日期：2016 年 10 月

Snyder 博士以其在水污染物分析与管理方面的工作和贡献获得了广泛的认可。他的研究集中在使用各种最先进的分析仪器，对已知及未知环境污染物的鉴定和定量分析方法进行研究和应用。而且，他的工作包括使用体外生物检定法分析水污染物的毒性效应。此外，Snyder 博士的工程研究集中在开发水处理技术，以最大限度降低能耗并最大程度改善水质。

Snyder 博士是国际杂志 Chemosphere 的主编，其因在应对全球水资源挑战方面的杰出工作于 2016 年被评选为国际水协会研究员。（新闻稿）

Rohit Bhargava 博士
Founder Professor of Engineering and Chemistry | Director, Cancer Center at Illinois
Depts. of Bioengineering, Electrical & Computer Sciences, Mechanical Science & Engineering, Chemical & Biomolecular Engineering and Chemistry
University of Illinois at Urbana-Champaign
Urbana, IL

获奖日期：2016 年 10 月

Bhargava 博士因其在红外光谱成像领域所做出的先驱工作而广受赞誉。他的工作包括提出有关红外成像的新颖理论和建模，以及研究其在光谱分析方面的应用。还包括展开仪器开发和计算方法方面的研究，以提取高保真信息以推动具有挑战性的研究。他的工作集中在生物医学科学的光谱成像应用，特别是癌症生物学和案例研究的临床应用。在他的实验室中开发的仪器已被用作新的表征工具，通过化学成像来定义癌症。（新闻稿）

Scott W. Lowe 博士
Chair, Cancer Biology & Genetics Program, Sloan Kettering Institute
Chair, Geoffrey Beene Cancer Research Center
Memorial Sloan Kettering Cancer Center
New York, NY

获奖日期：2016 年 8 月

Lowe 博士的研究为我们理解 p53、APC 以及 PTEN 等数种关键肿瘤抑制基因做出了贡献。同样，他成功建立了无数遗传筛选和动物模型，在新型目标药物的鉴定和表征，以及确定对新疗法可能比较敏感的癌细胞的易感性方面发挥了重要作用。其中某些筛选和动物模型已经在广泛使用 shRNAi 文库。最近，Lowe 博士采用 CRISPR/Cas 9 进一步发掘了这项技术的优势，以增进我们对癌症的理解和管理。（新闻稿）

Peter Robinson 博士
Professor of Computational Biology
The Jackson Laboratory for Genomic Medicine
Farmington, CT

获奖日期：2016 年 2 月

Robinson 博士以开发人类表型本体（人类疾病中遇到的表型异常的标准化词汇）而闻名，并且他创建了用于鉴定各种新的疾病基因的方法。Robinson 博士曾就读于哥伦比亚大学数学与计算机科学专业和宾夕法尼亚大学医学专业。他在柏林自由大学和大学附属夏里特 (Charité) 医院完成了儿科医师实习。（新闻稿）

Shilin Chen 博士 
Director, Institute of Chinese Materia Medica,
China Academy of Chinese Medical Sciences
Beijing, China

获奖日期：2016 年 2 月

陈博士是北京中国中医科学院中药研究所的负责人。他主要从事天然产物的药物化学领域的研究工作，该研究涉及到中药活性成分鉴定及其作用机制的确定，得到了学术界的高度认可。研究包括但不限于青蒿素等抗疟系列药物。同样，陈博士率先采用基因组方法（如 NGS 测序和 DNA 条形码）进行药用植物物种的鉴定。（新闻稿）

Jeffrey I. Gordon 博士 
The Dr. Robert J. Glaser Distinguished University Professor and
Director of the Center for Genome Sciences & Systems Biology
Washington University School of Medicine
St. Louis, MO

获奖日期：2015 年 10 月

Gordon 博士是全球公认的微生物组研究领域的先驱和领导者。他的成就，包括极具影响力的 2005 年度 NHGRI 白皮书，题目为“扩展我们对自身的认识：人类肠道微生物倡议 (HGMI)”，并因此获得了 2007 年创立的 NIH“用于医学研究的人类微生物组计划路线图”基金。Gordon 博士的研究方向主要为研究人类与胃肠道中的数万亿共生菌之间的互利关系。他的研究采用了无菌小鼠作为宿主模型，并采用宏基因组学、代谢组学、微生物学、生物化学和营养科学等手段研究人类肠道微生物组成及它们对人类健康和发育的影响。他和他的团队特别关注与营养不良、肥胖以及神经和免疫调节及发育有关的领域。（新闻稿）

Lawrence J. Lesko 博士 
Department of Pharmaceutics
College of Pharmacy
University of Florida,
Orlando, Florida

获奖日期：2015 年 3 月

Lesko 博士是位于诺娜湖的佛罗里达大学药学院药物计量学与系统药理学中心主任。在加入佛罗里达大学 (UF) 之前，Lesko 博士曾在美国食品药品监督管理局 (FDA) 药物评估和研究中心担任临床药理学办公室主任近二十年。他曾是 FDA 的医疗政策协调委员会临床药理学协调分会的主席，撰写或与人合著了众多的行业指南，并启动了 FDA 的自愿基因组数据提交计划和药物安全机制计划。（新闻稿）

Arturo A. Keller 博士
Department of Environmental Biogeochemistry
Bren School
University of California, Santa Barbara
Santa Barbara, CA

Awarded March 2015

Arturo Keller 博士是加州大学圣塔芭芭拉分校纳米技术环境影响中心的负责人。他凭借天然水和土壤中纳米颗粒的吸收、积累与生物转化研究获得了国际认可。他研究的一项重点是分析纳米颗粒以便将其安全、可持续地引入农业产业。（新闻稿）

Jules Griffin 博士
Department of Biochemistry
University of Cambridge
United Kingdom

获奖日期：2014 年 9 月

Jules Griffin 博士是伦敦帝国学院名誉教授， 国王学院院士，剑桥大学生物化学系高级讲师。他还领导了 MRC 脂质分析和信号传导计划。他专注于研究利用高分辨率质谱仪测量生物体液和组织提取物中的脂类以更好地了解 2 型糖尿病和肥胖症（通常也被统称为代谢综合征）的病因和后果，并开发了用于存储和处理这些实验产生的大量数据的计算机软件工具。（新闻稿）

Carlos Cordon-Cardo 博士
The Irene Heinz Given and John LaPorte Given Professor
and Chair of Pathology for the Mount Sinai Health System
Dept. of Pathology
The Mount Sinai Hospital
New York, NY

Awarded: August 2014

Cordon-Cardo 博士是一位杰出的临床医生和研究人员，他开创性地研究了实验病理学和分子肿瘤学，并得到了国际上的认可。他的研究集中于分析人类癌症中肿瘤抑制基因的多药耐药和改变，以及人类癌症干细胞的分离和表征。他还为肿瘤分子病理学学科的发展和实施作出了贡献，并帮助创建了“系统病理学平台”。（新闻稿）

Carolyn Mountford 博士
Centre for MR in Health
School of Health Sciences
Faculty of Health and Medicine
University of Newcastle
Australia

Awarded: April 2013

Mountford 博士是澳大利亚纽卡斯尔大学健康科学学院和哈佛医学院的放射学教授。她是纽卡斯尔大学临床研究核磁共振中心的负责人，同时也是波士顿布列根和妇女医院临床光谱中心的负责人。Mountford 博士的代表性贡献是创新性地将核磁共振 (NMR) 光谱技术用于癌症研究。（新闻稿）

John A. McLean 博士
Stevenson Professor
Department of Chemistry
Vanderbilt University
Nashville, TN

Awarded: March 2014

在范德堡大学的化学系，McLean 教授和他的同事致力于结构质谱仪的构想、设计和建造，特别是针对系统生物学、合成生物学、化学生物学以及纳米技术中的复杂样品的研究。他的研究小组将这些策略应用到最前沿转化研究领域，该研究领域主要涵盖药物发现、个体化医疗以及“人类芯片”合成生物学平台。（新闻稿）

Joshua D. Rabinowitz 博士
Professor of Chemistry and Integrative Genomics
Princeton University
Princeton, NJ

Awarded: October 2013

Rabinowitz 博士为代谢组学领域做出了开创性的概念和方法学上的贡献。这些贡献包括同位素标记、样品前处理、数据分析和适用于液质联用系统数据的信息可视化技术的开发。（新闻稿）

Paul B. Watkins 博士
Professor of Medicine, Toxicology, and Experimental Therapeutics
Director, Institute for Drug Safety Sciences
The Hamner Institutes for Health Sciences
Research Triangle Park, NC

Awarded: October 2013

Paul B. Watkins 医学博士是北卡罗来纳大学教堂山分校 (UNC) 的医学、毒理学与实验治疗学教授，也是药物安全科学研究所的主任。Watkins 博士是国际公认的药物安全方面的专家，具有丰富的药源性肝脏损伤 (DILI) 研究经验，研究内容包括药物代谢与转运方面的基础研究、临床研究、因果关系评估和法规事务。（新闻稿）

Junying Yuan 博士
Director of the Interdisciplinary Research Center on Biology
Chinese Academy of Science
Shanghai, China

Awarded: November 2013

Junying Yuan 博士是细胞凋亡研究领域的先驱和顶尖研究人员。“安捷伦思想领袖奖”将大力支持在中国科学院新成立的生物与化学跨学科研究中心进行的鉴定神经退行性疾病的生物标记物的代谢组学和系统生物学研究。（新闻稿）

Guibin Jiang 博士
Director of State Key Laboratory of Environmental Chemistry and Ecotoxicology
Chinese Academy of Sciences
Haidian District,
Beijing, China

Awarded: October 2013

江博士主要致力于分析化学和环境化学的研究。他系统全面的研究成效显著，研究包括：持久性有机污染物 (POP) 的分析方法开发和环境表征、以及有机金属化合物的形态分析，他的研究为中国这类科学领域的改善和国际化做出了重要贡献。（新闻稿）

Emmanuel Barillot 博士
Director of Bioinformatics and Systems IT
Institut Curie
Paris, France

Awarded: August 2013

Barillot 博士的工作领域是开发细胞信号通路的数据库以及促进制药行业研发出更高效的癌症治疗方法的可视化工具。（新闻稿）

Hashim Al-Hashimi 博士
J. Lawrence Oncley Collegiate Professor of Chemistry and Biophysics
Dept. of Chemistry and Biophysics
University of Michigan
Ann Arbor, MI

Awarded: March 2013

Hashim Al-Hashimi 博士是一位在结构生物学领域颇具影响力的研究人员。Al-Hashimi 博士和他的团队在密歇根大学 进行 Hoogsteen 碱基对高级表征方法的开发，他利用核磁共振光谱对一种与典型的双螺旋结构不同的罕见 DNA 进行表征。Hoogsteen 碱基对以生物化学家 Karst Hoogsteen 的名字命名，因其不同寻常的结构和生物功能而备受关注。Al-Hashimi 博士和他的团队相信通过他们的研究能够显著推动 DNA 靶向药物发现和其他应用的发展。（新闻稿）

Ronald DePinho 医学博士
President, MD Anderson Cancer Center
University of Texas
Houston, TX

Awarded: December 2012

Ronald A. DePinho 博士，世界著名的肿瘤学家和研究人员，荣获安捷伦思想领袖奖，此项奖励将用于表彰他在癌症早期阶段代谢物重编程的研究。他对于癌症、衰老和与年龄相关的退行性疾病的基础及转化研究得到了国际的认可。他是安德森 70 年历史上唯一一位四次当选的全职主席。（新闻稿）

Robert Gerszten 医学博士
Director of Clinical and Translational Research
Institute for Heart, Vascular and Stroke Care
Massachusetts General Hospital
Boston, MA

Awarded: November 2012

Robert E. Gerszten 博士荣获安捷伦思想领袖奖，以表彰其在心血管及相关代谢疾病中代谢物生物标记物发现的研究。Gerszten 博士率先使用蛋白质组学和代谢组学方法，通过弗雷明汉心脏队列研究来鉴定这些疾病的生物标记物。（新闻稿）

Dr. Jens Frisvad
Professor, Department of Systems Biology
Center for Microbial Biotechnology
Technical University of Denmark
Lyngby, Denmark

Awarded: May 2012

Frisvad 教授主要从事真菌研究。其研究方向主要为霉菌的生化多样性，致力于发现可用于药物的新酶和次级代谢产物。此外，他还进行关于青霉菌和曲霉属真菌的真菌毒素及霉菌的研究，试图找到办法防止食物、室内环境和生物技术产品中产生毒素。（新闻稿）

Russell Thomas 博士
Senior Investigator
Director, Institute for Chemical Safety Sciences
Director, Center for Genomic Biology and Bioinformatics
Hamner Institutes for Health Sciences

Awarded: December 2011

Russell S. Thomas 博士来自哈姆纳健康科学研究院，他被授予安捷伦思想领袖奖。此奖项用于支持其开发预测药物导致肝损害的方法。这个奖项包含安捷伦科技基金会提供的经费以及安捷伦公司提供的仪器，包括一套 6460 三重四极杆液质联用系统和一台安捷伦微阵列芯片扫描仪。Thomas 博士是哈姆纳化学安全科学研究院主任。此研究院正致力于应用一种系统生物学方法预测药物导致的肝损害。（新闻稿）

Chris Evelo 博士
Department Head, Bioinformatics BiGCaT
Maastricht University
Maastricht, Netherlands

Awarded: November 2011

马斯特里赫特大学生物信息学系的 Chris Evelo 博士荣获了安捷伦思想领袖奖，以表彰他在开发用于整合不同类型生物数据的软件中所做出的贡献。该奖项的目的在于通过推进系统生物学方法的整合来帮助加快疾病研究的突破性进展。Evelo 实验室帮助开发了用于构建多组学数据的社区策划平台 — WikiPathways.org，以及相关开放式通路分析工具 PathVisio。（新闻稿）

Steven Carr 博士
Senior Scientific Leader, Protein Biochemistry and Proteomics
Broad Institute
Cambridge, MA

Awarded: October 2011

Steven Carr 博士就职于布罗德研究所（隶属于麻省理工学院和哈佛大学），荣获安捷伦​​思想领袖奖。该奖项将用于表彰 Carrs 在蛋白质和多肽分析新技术开发研究方向做出的努力，他的研究旨在帮助医生诊断疾病，如心血管疾病、乳腺癌和卵巢癌。（新闻稿）

Gerhard Wagner 博士
Department of Biological Chemistry and Molecular Pharmacology
Harvard Medical School
Boston, MA

Awarded: August 2011

Gerhard Wagner 博士就职于哈佛医学院生物化学与分子药理学系，荣获安捷伦思想领袖奖，该奖项用以表彰他对现代结构生物学工具构成严峻挑战的生物相关系统研究的方法开发方面所做的努力。Wagner 教授的研究工作将极大提高 NMR 光谱在大型蛋白质的分配和结构鉴定方面的影响，NMR 光谱通过现代高场仪器的功能与合适的采集和处理方法相配合进行蛋白质研究。 （新闻稿）

Adam Arkin 博士
Director, Synthetic Biology Institute
Dean A. Richard Newton Memorial Professor,
Department of Bioengineering
University of California, Berkeley
Director, Physical Biosciences Division, Lawrence Berkeley National Lab

Awarded: April 2011

Adam Arkin 是 SBI（合成生物学研究所）和劳伦斯伯克利国家实验室物理生物科学部主任，加州大学伯克利分校生物工程系 Dean A. Richard Newton 纪念教授。他也是微生物压力和生存虚拟研究所的联合主管，联合生物能源研究所生物信息学主任，以及 BIOFAB（国际前沿生物技术开放实验室）的联合主管。他的研究集中于揭示蜂窝网络和种群的进化设计原则，并将其进行开拓应用。他和同事正通过将比较功能基因组学、细胞动力学的定量测定、蜂窝网络的生物物理建模以及蜂窝式电路设计结合起来，开发一种可促进健康、环境和生物能源应用的框架。（新闻稿）

Bart Weimer 博士
Professor, Population Health & Reproduction
School of Veterinary Medicine
University of California, Davis

Awarded: January 2011

Weimer 博士的实验室团队在兽医学院专注于微生物生理和功能的研究。他们通过研究宿主/微生物相互作用，阐释了益生菌与肠道上皮细胞的竞争性结合，以及致病菌（例如，沙门氏菌）的移位。通过使用基因组学和功能基因组学基因表达、代谢组学、蛋白质组学以及宏基因组学，Weimer 博士的研究计划考察了基因相互作用以产生特定表型的机制，以及过程中涉及的新陈代谢。

David Botstein 博士
Lewis-Sigler Institute for Integrative Genomics
Princeton University

Awarded: November 2010

Dr. David Botstein, professor and director of the Lewis-Sigler Institute for Integrative Genomics and the Center for Quantitative Biology at Princeton University, received an Agilent Thought Leader award in support of his research in the area of genomics. This award of cash funding and Agilent products to the Lewis-Sigler Institute for Integrative Genomics will allow Dr. Botstein to produce the most complete genomic, proteomic and metabolomic data sets from any eukaryote (organism with cells containing membrane-enclosed structures including nucleus) to date. (press release)

Hailu Kinde 博士，预防兽医学硕士，兽医学博士
UC Davis School of Veterinary Medicine California Animal Health and Food Safety Laboratory

Awarded: October 2010

Dr. Hailu Kinde, professor at the California Animal Health and Food Safety Laboratory System, received an Agilent Thought Leader award in support of his research in the area of food safety. This award of cash funding and Agilent products to the UC Davis School of Veterinary Medicine will allow Dr. Kinde to focus on the development of a new process that can reduce the time required to identify food-borne pathogens from several days to only a few hours. (press release)

Thomas Hartung 博士
Director for the Center for Alternatives to Animal Testing (CAAT)
Bloomberg School of Public Health
Johns Hopkins University

Awarded: August 2010

Dr. Thomas Hartung received an Agilent Thought Leader award in support of his research on for the use of toxicity pathways to predict developmental neurotoxicity. Through this award of funding from the Agilent Foundation and a company donation of instruments to the Center for Alternatives to Animal Testing (CAAT) at the Johns Hopkins Bloomberg School of Public Health, Dr. Hartung will focus his research on the identification of novel toxicity pathways by combining two promising cell culture models with emerging metabolomics. This work could help identify possible contributions of chemicals to disorders such as autism and attention hyperactivity disorders. (press release)

James Collins 博士
Professor of Biomedical Engineering
Wyss Institute for Biologically Inspired Engineering

Awarded: July 2010

James Collins 博士正在开发对生物体（特别是细菌）进行重新编程的创新方法，以便执行所需的任务，比如攻击肿瘤和引导干细胞的发育。这些编程后的细菌使得药物更加便宜，燃料更加环保，同时还能对抗生素耐药性引起的感染和疾病实现更有效的治疗。他是系统生物学、随机共振、生物动力学和神经刺激研究领域的先驱，他的目标是改善生理和生物系统的功能。（新闻稿）

George Church 博士
Professor of Genetics
Harvard Medical School
Director of the Center for Computational Genetics
Wyss Institute for Biologically Inspired Engineering
Boston, MA

Awarded: July 2010

Dr. George Church is Professor of Genetics at Harvard Medical School and Director of NIH-CEGS and DOE-GTL Genomics Centers. He has pioneered technology innovations early in the development of key fields in chemistry and biomedicine with 10 US Patents granted and several pending. As part of technology transfer to the commercial sector he has served on 22 scientific advisory boards. In 1976, his crystallographic software lead to the first high-resolution folded-RNA structure (a decade before similar structures important for ribozymes, aptamers, and RNAi). (press release)

Don Ingber 博士
Wyss Institute Founding Director
and Core Faculty Member
Platform Leader, Biomimetic Microsystems

Awarded: July 2010

Dr. Ingber is Founding Director of the Wyss Institute and a leader in the emerging field of biologically inspired engineering. He oversees a multifaceted effort to identify the mechanisms that living organisms use to self assemble and to apply these design principles to develop advanced materials and devices. Dr. Ingber was the first researcher to recognize that tensegrity architecture (in which a system stabilizes itself mechanically by balancing local compression with continuous tension) is a fundamental principle in the way living organisms are structured at the nanometer scale. (press release)

Janne Lehtio 博士
Karolinska Institute
Department of Oncology-Pathology
Science for Life Laboratory

Awarded: June 2010

Dr. Janne Lehtio has worked on clinical proteomics both in academia and biotech industry. In 2004, Dr. Lehtio was selected to build mass spectrometry based proteomics at Karolinska University Hospital and continues his proteomics research there. Today, Dr. Lehtio leads a mass-spectrometry-based proteomics group at Karolinska Institutet focusing on quantitative proteomics methods development and cancer proteomics. In recent year his lab has developed several methods for clinical proteomics and currently uses these methods to understand proteome changes related to cancer therapy.

Pauline Rudd 博士
Professor of Glycobiology
University College Dublin
National Institute for Bioprocessing Research and Training (NIBRT)

Awarded: May 2010

Dr. Pauline Rudd received an Agilent Thought Leader award in March 2010 in support of emerging glycomics research through a grant of funding and instruments to the National Institute for Bioprocessing Research and Training (NIBRT) at the University College Dublin in Ireland. The goal of the research is to develop novel approaches to analyze protein glycosylation as part of the characterization process of recombinant protein drugs and to study disease glycan biomarkers using liquid chromatography mass spectrometry. (press release)