Direct scale-up from method scouting to gram-level purification
1290 Infinity II Autoscale Preparative LC/MSD System
LC/MSD for purification enables highly selective detection and identification of compounds based on their mass-to-charge ratio, particularly useful for purifying complex mixtures. The technique can be integrated into automated workflows, enhancing efficiency. The 1290 Infinity II Autoscale Preparative LC/MSD System combines liquid chromatography’s separation capabilities with mass spectrometry’s precision, facilitating highly selective and efficient compound separation for direct scale-up from analytical scouting to gram-level purification of target compounds.
Agilent automated purification software for Agilent OpenLab CDS ChemStation edition facilitates seamless method transfer from analytical to preparative-scale purification. With mass-selective fraction triggering, the software streamlines your purification workflows and boosts laboratory efficiency.
Agilent automated purification software for Agilent OpenLab CDS ChemStation edition facilitates seamless method transfer from analytical to preparative-scale purification. With mass-selective fraction triggering, the software streamlines your purification workflows and boosts laboratory efficiency.
Product Details
Features
- Automated, combined sample injection and fraction collection enable automated scale-up from analytical to preparative HPLC on a single analytical to preparative system to maximize purity and your capacity to increase your daily throughput.
- Support of automated workflows through import and export of HPLC sample sequences while focusing solely on your target compounds to minimize reanalysis time and reformulation of collected fractions.
- Highly reliable and robust automated purification system for LC/MS improves your ability to manage an ever-increasing workload demand.
- Easy-to-change pump heads provide a dynamic flow range up to 200 mL/min at a maximum of 600 bar for versatile application within a wide range of preparative workflows.
- Upgradeable fraction capacity based on your demand.
- Integrated and automated fraction delay sensor technology for increased purity and recovery of collected fractions.
- Control and organization of valves: five multipurpose slots provide enhanced organization of valves, fraction delay coils, and Agilent 1290 Infinity II MS Flow Modulator for a significant increase in productivity.
- Integration of all standard collection modes and compatibility with multiple trigger sources provides compatibility with existing purification methods.
- Lowest delay volume to minimize peak dispersion and carry-over for excellent HPLC sample recovery and purity.
- Clean software infrastructure through Agilent OpenLab CDS ChemStation edition for familiar and reliable operation.
- Automated purification software opens the door to workflow automation to scale-up from analytical to preparative conditions based on scientific algorithms, eliminating the need for time-consuming method development to improve daily purification cycles
- Integrated leak sensor in each module shuts down the whole preparative HPLC system, providing additional safety when detecting a leak.
How It Works
Applications
