One HPLC autosampler with two injection modes
1260 Infinity III Hybrid Multisampler
For samples with strong solvent, for example after QuEChERS sample preparation in food analysis, sample solvent effect is a challenge that leads to peak break through and poor peak shapes, especially as injection volumes increase. Agilent Feed Injection can mediate the strong sample solvent effect by mixing sample and mobile phase directly at injection to improve peak shapes and sensitivity. By applying Feed Injection mode, there is no need for extra sample preparation, and the perfect peak shapes enable easy peak integration.
- HPLC Injectors
Product Details
- Hybrid injection technology allows both classical flow-through injection for seamless method transfer and Agilent Feed Injection to mediate strong sample solvent effects and improve peak shapes in HPLC
- Shallow microplate drawers take a maximum load of 16 microplates and up to 6,144 samples for unmatched sample capacity
- Robotics move microplates and other sample containers from sample hotel to central workspace for seamless automation during sample processing steps and injections
- Three individual wash options (inner wash, outer wash, and seat wash) with multiple solvents enable low carryover
- Integrated sample thermostat, available as option or upgrade, provides cooling and heating from 4 to 40 °C
- Lights on each drawer indicate loading status, current activity, and accessibility for instant information
- Application Notes
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Improved Peak Shape and Lower LOQs in Pesticide Analysis
This application note demonstrates the use of the Agilent 1260 Infinity II Hybrid Multisampler in Agilent Feed Injection mode for the multiresidue LC/MS analysis of polar pesticides dissolved in strong eluting organic solvent.
- Application Notes
- English
- 14 Oct 2024
- 2.00 MB
More Sensitive Quantification of PFAS by LC/MS with the Agilent 1260 Infinity II Hybrid Multisampler
In this application note, the sensitive quantification of PFAS by LC/MS is described, using the Agilent 1260 Infinity II hybrid multisampler.
- Application Notes
- English
- 14 Oct 2024
- 1.02 MB
Quality Control of Lithium-Ion Battery Electrolytes Using LC/MS
In this application note, a method was presented to quantify major components as well as degradation products of lithium-ion battery electrolytes, with particular attention to achieving separation of all analytes within 14 minutes.
- Application Notes
- English
- 14 Oct 2024
- 782.05 KB
- FAQs
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An Introduction to the Fundamentals of the 1260 Infinity II Hybrid Multisampler, FAQ
Learn about the basics of the 1260 Infinity II Hybrid Multisampler, which features classic flow-through and Agilent Feed Injection modes. Read frequently asked questions (FAQs) on the Feed Injection principle, its benefit for strong sample analysis, how to reduce carryover, and how to get better analysis results. You can also contact our specialists to find out how Agilent can help with your strong solvent effect challenges.
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Dr. Matthias Pursch
R&D, Dow
The Agilent Hybrid Multisampler with Feed Injection mode is a powerful option to help overcome the strong solvent effect challenges.
View MoreVideos
Start-to-Finish Workflows for PFAS Analysis: Meet the Challenges of a Regulated Landscape
Get the answers to FAQs about per- and polyfluoroalkyl substances (PFAS). Plus, learn how Sanexen Environmental Services have optimized their end-to-end PFAS workflows. Also, listen to experts at Weck Laboratories address the challenges of low-level quantitation when analyzing PFAS.
- 15 Jan 2024